What is CHS?
Triggered by high THC exposure, Cannabinoid Hyperemesis Syndrome (CHS) causes a constellation of symptoms including chronic nausea and vomiting, abdominal pain and hot bathing behavior for relief.
How does one develop CHS? What is the cause?
Cannabinoid Hyperemesis Syndrome is triggered by high THC exposure. Russo, et al published a small genomic study of 28 confirmed CHS patients and 12 controls to discover that 5 genes appear to be high statistically significant in contributing to one’s susceptibility to CHS. All 28 confirmed CHS patients had at least two of the five genes.
What are the symptoms of CHS?
Symptoms generally occur within 48 hours of THC exposure and vary widely but most notably include abdominal pain, persistent nausea and vomiting relieved by hot bathing and for some, relief is attained by application of capsaicin cream to the skin. Additional symptoms include other gastrointestinal upset, anxiety, depression, food and odor sensitivities. Depending on the severity of one’s case, they may become dehydrated (some dangerously so), develop a fear of vomiting, weight loss, chills, constipation, diarrhea and burping.
Who can help diagnosis what is wrong with me?
Internists, gastroenterologists, emergency physicians and cannabis physicians are most likely to be familiar with the signs and symptoms of CHS. Ask your physician to order this DNA susceptibility kit to see if you are genetically predisposed to CHS.
Is CHS terminal or life threatening?
When treated, CHS is not terminal nor life threatening. However, at least two CHS patients have died as a result of complications associated with severe vomiting accompanying the disorder. It is important to remain hydrated most especially when in the hyperemetic phase of the condition.
What can I do to feel better?
STOP using cannabis! This is a must for anyone who wants to feel better.
It is also important to ensure you hydrated sufficiently, get exercise, eat a healthy diet absent (or low in) fast and processed foods, sugar replacements/substitutes and high volumes of processed sugar and that you engage in non-cannabis activities that bring you joy.
Are there treatments for CHS?
Different treatments seem to work better on different people. Click here to learn about the treatments that appeared to be helpful in the study conducted by Russo et al.
Will I ever be able to use cannabis again?
Probably not. The answer to this question requires significantly more research. Many CHS patients came to cannabis for medical reasons and would like to be able to consume other cannabinoids to treat their ailments. It is possible that non-THC products made from isolated cannabinoids are safe for some CHS suffers to consume, but it is very difficult to know without additional research.
When can I expect to feel better?
Patients who abstain from Cannabis use may begin to feel better in the first 24-48 hours of cessation. However, some people have reported ongoing symptoms for months after stopping THC use and some have reported ongoing symptoms for up to a year after.
How long will CHS last?
It varies by the individual. Based on existing clinical evidence, it is likely that once triggered, one will always be at risk for experiencing CHS symptoms anytime they consume THC. Some patients have reported being able to consume cannabis for a short period of time without issue but eventually, the symptoms return. For those who abstain from THC use, once they are in the recovery phase and become symptom free, they will likely remain symptom free until THC is ingested.